Journal: Current colorectal cancer reports

Article Title: Diet, Gut Microbiota, and Colorectal Cancer Prevention: A Review of Potential Mechanisms and Promising Targets for Future Research

doi: 10.1007/s11888-017-0389-y

Figure Lengend Snippet: Summary of epidemiologic studies examining the association of the fecal microbiome with colorectal cancer

Article Snippet: 15 Given the critical role of diet in the configurations of gut microbial communities and production of bacterial metabolites, it has been proposed that diet may influence CRC risk through modulation of the gut microbial composition and metabolism that in turn shape the immune response during tumor development. table ft1 table-wrap mode="anchored" t5 caption a7 Author, Year Country Study Design Sample Size Main Findings Comparing Cases to Controls Scanlan, 2008 3 Belgium Case-control 20 cancers / 20 polyps / 20 controls ↑ diversity of the Clostridium leptum and C. coccoides subgroups Sobhani, 2011 4 France Case-control 60 cancers / 119 controls ↑ Bacteroides/Prevotella Wang, 2012 5 China Case-control 46 cancers / 56 controls ↑ Bacteroides fragilis and opportunistic pathogens; ↓ butyrate-producing bacteria Ahn, 2013 6 USA Case-control 47 cancers / 94 controls ↓ diversity; ↓ Clostridia ; ↑ Fusobacterium , Porphyromonas ; Zackular, 2014 7 USA Case-control 30 cancers / 30 adenomas / 30 controls ↑ Bacteroides fragilis, Fusobacterium , Porphyromonas ; ↓ butyrate-producing bacteria Zeller, 2014 8 France Case-control 91 cancers / 42 adenomas / 358 controls ↑ Bacteroidetes , Fusobacteria and Proteobacteria ; ↓ Actinobacteria and Firmicutes Feng, 2015 9 Austria Case-control 41 cancers / 42 adenomas / 55 controls ↑ B. dorei, B. vulgatus, E. coli, Fusobacterium; ↓ Lactobacillus and Bifidobacterium Vogtmann, 2016 10 USA, France Case-control 52 cancers / 52 controls ↑ Fusobacterium, Porphyromonas, Clostridia Yu, 2017 11 Denmark, France, Austria Case-control 74 cancers / 54 controls ↑ Peptostreptococcus stomatis , F. nucleatum, Parvimonas micra, Solobacterium moorei Shah, 2017 12 Multiple countries Pooled analysis of case-control studies 195 cancers / 79 adenomas / 235 controls ↑ Parvimonas micra ATCC 33270, Streptococcus anginosus , yet-to-becultured members of Proteobacteria Liang, 2017 13 China Case-control 203 cancers / 236 controls ↑ F. nucleatum, Clostridium hathewayi; ↓ B. clarus Flemer, 2017 14 Ireland Case-control 43 cancers / 37 controls ↓ Lachnospiraceae incertae sedis and Coprococcus Open in a separate window Summary of epidemiologic studies examining the association of the fecal microbiome with colorectal cancer Overall, the gut microbiome exhibits substantial inter-individual variation but high overall temporal stability within individuals.

Techniques: Bacteria

Journal:

Article Title: Apparent Culture-Negative Prosthetic Valve Endocarditis Caused by Peptostreptococcus magnus

doi:

Figure Lengend Snippet: Growth of peptostreptococci in BacT/Alert FAN anaerobic and aerobic blood culture media, Thioglycollate Medium, and Columbia Broth supplemented with 5 ml of horse blood

Article Snippet: Subcultures from culture-negative bottles were made on days 3, 7, and 14 on blood agar and incubated anaerobically for up to 96 h. table ft1 table-wrap mode="anchored" t5 TABLE 1 caption a7 Microorganism Isolate BacT/Alert FAN anaerobic (FN) BacT/Alert FAN aerobic (FA) TM/CB c growth (day) Signal a (day) Culture b (day) Signal a (day) Culture b (day) P. anaerobius AMC B10g8 No Neg No Neg 3 P. anaerobius AMC D24d8 No Neg No Neg 3 P. anaerobius ATCC 27337 No Neg No Neg 5 P. magnus AMC G9g1 No Neg No Neg 3 P. magnus AMC G11a2 No Neg No Neg 3 P. magnus ATCC 29328 No Neg No Neg 3 P. asaccharolyticus AMC B10h3 1 1 No Neg 3 P. asaccharolyticus AMC B10h4 1 1 7 7 3 P. asaccharolyticus ATCC 29743 1 1 No Neg 3 P. micros AMC A3e4 6 6 No Neg 3 P. micros AMC B10h2 2 2 6 6 3 P. micros ATCC 33270 2 2 No 14 3 P. productus ATCC 27340 1 1 No Neg 5 Open in a separate window a Automated detection by the BacT/Alert system for 14 days. microorganisms were reconfirmed after subculture.

Techniques: